MJPRRS® Technologies

What we know about protection against PRRSV
  • PRRS MLV vaccine provides protection against homologous PRRSV.
  • The conventional killed vaccine is not demonstrating effectiveness.
  • Serum injection has not been always effective for PRRS outbreak.
  • Clinical protection against heterologous PRRS virus has not been established.
Tech. #1 ; Grouping viruses
  • Sort PRRSVs based on immunological properties
  • Select right viruses for vaccine
Tech. #2 ; Vaccine production
  • Time-course study for optimal harvesting time to maximize major envelope proteins contents
  • Apply MJPRRS process technology
Dilemmas
  • Dendogram did not match to observation at the field.
    • D-Lab Report says "there were 16% difference between two isolates, but there was no clinical sign much"
    • D-Lab Report says "there were less than 1% difference between two isolates, but it caused huge clinical sign, a lot of abortion"
  • RFLP of PRRSVs did not explain why outbreak occurred back to back in short time period.

Blocking Viral Attachment on Host Cells prevents the disease!!! Figure 1
How can Pig cells prevent virus-attachment?
→Need Abs against viral surface proteins, especially ORF-5 Protein.


2. Location of Amino acid Change Figure 2

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MJPRRS Vaccine works because


  1. 1. Concentrated viral component antigen effect
  2. 2. Full Monty Effect
    Figure 9
  3. 3. It may trigger diffrent immune response.


Figure 2

Better Control and Management

MJPRRS Vaccine:
  • Autogenous killed vaccine. (No Risk)
  • Five virus strains in each vaccine. (Broader Protection)
  • Proprietary technology to identify specific virus strains to your farm. (Specific Protection)
  • Proprietary manufacturing technology producing more diverse antigens. (More Complete Antibody Repsonse)

MJPRRS Vaccine Usage

This is an autogenous killed PRRS Vaccine.
  • Regulated by the USDA.
  • This is used only thru licensed veterinarians.
  • Each farms is unique in health status, management practices, and production facilities consult with your veterinarian for use in the sow herd and grow-finish production.
  • Recommended to be used on positive or primed pigs.
  • Priming can be completed via;
    • Serum
    • Natural Exposure
    • MLV